Pharmacological effects of ofloxacin

Pharmacological effects of ofloxacin

Ofloxacin Basic information

Product Name: Ofloxacin
Synonyms: (+/-)-9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid;AKOS NCG1-0050;floxin;oflx;OFLOXACIN;(-)-(s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;TARIVID;(+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
CAS: 82419-36-1
MF: C18H20FN3O4
MW: 361.37
EINECS: 680-263-1
Product Categories: Antibiosis;API;Ofloxacin;1694 Pharmaceuticals&Personal Care Products;Pharmaceutical intermediate;FLOXIN;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Alphabetic;EPA;NeatsAnalytical Standards;O;Peptide Synthesis/Antibiotics;Active Pharmaceutical Ingredients

Ofloxacin is a white to slightly yellow crystalline powder; it is odorless; it changes color when exposed to light. This product is slightly soluble or very slightly soluble in water or methanol; easily soluble in glacial acetic acid or sodium hydroxide test solution, and soluble in 0.1mol/L hydrochloric acid solution. Specific rotation: take this product, accurately weigh it, add chloroform to dissolve and dilute quantitatively to make a solution containing about 10mg per 1ml, measured according to law (General Rule 0621), the specific rotation is -1° to +1°

Pharmacological action

Ofloxacin has the characteristics of wide antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against Gram-negative bacteria, and has good antibacterial effect against Gram-positive bacteria, Legionella, Mycoplasma, and Chlamydia, but it has a good antibacterial effect against gram-negative bacteria. Oxygen bacteria and enterococci are less effective.